The number of COVID-19 cases and deaths has continued to decline globally, with 3.1 million new cases and just over 54,000 new deaths, reported over the last week, according to the World Health Organization (WHO).
Compared to the previous week, this represents a nine per cent decrease in cases, while deaths remained similar, the WHO said in its weekly epidemiological update. This continues the trend that has been observed since August.
During the week of 27 September to 3 October, all regions reported a decline in the number of new cases, apart from Europe which remained similar to the week before.
The largest decrease in new weekly cases was reported in Africa (43 per cent), followed by the Eastern Mediterranean (21 per cent), Southeast Asia (19 per cent), the Americas (12 per cent) and the Western Pacific (12 per cent).
4.8 million deaths
The number of confirmed cases reported globally is now over 234 million, with fatalities just under 4.8 million.
A large decline in the number of new weekly deaths was also reported for all regions, except the Americas and Europe. These regions both reported a similar number of weekly deaths as the previous week.
The largest decline in weekly deaths was reported from Africa, with a 25 per cent decline, compared with the previous week.
According to the update, the regions reporting the highest weekly case incidence rates per 100,000 population were Europe (123.1 new cases per 100,000) and the Americas (109.5 new cases per 100,000), while the same two regions reported this highest weekly incidence in deaths per 100,000 population; the Americas (2.4 new cases per 100,000) and Europe (1.6 new cases per 100,000).
US leads new cases
The highest numbers of new cases were reported from the United States (760,571), the United Kingdom (239,781 new cases; similar to the number reported in the previous week), Turkey (197,277 new cases; similar to the number reported in the previous week), the Russian Federation (165,623 new cases; 13 per cent increase), and India (161,158 new cases; a 21 per cent decrease).
Globally, the report found that cases of the Alpha variant have been reported in 195 countries, territories or areas (two new countries added since last week), while 145 countries (3 new countries since last week) have reported cases of the Beta variant; and 99 countries have reported cases of the Gamma variant (4 new countries since last week).
The Delta variant has been reported in 192 countries (seven new countries since last week) across all six WHO regions, as of 5 October.
UN-backed COVAX mechanism delivers its 1 billionth COVID-19 vaccine dose
With a 1.1 million jab delivery in Rwanda this weekend, the World Health Organization’s multilateral initiative to provide equal access to vaccines for all reached the one billion milestone.
Along with the Coalition for Epidemic Preparedness Innovations (CEPI), the Vaccine Alliance GAVI, and partners, WHO has led the largest vaccine procurement and supply operation in history with deliveries to 144 countries to date.
According to a press release published on Sunday, as of 13 January 2022, out of 194 countries members of WHO, 36 have vaccinated less than 10% of their population, and 88 less than 40%.
“COVAX’s ambition was compromised by hoarding/stockpiling in rich countries, catastrophic outbreaks leading to borders and supply being locked. And a lack of sharing of licenses, technology, and know-how by pharmaceutical companies meant manufacturing capacity went unused”, the agency explained.
On 24 February 2021, Ghana became the first country in the world to receive vaccines through COVAX when 600,000 doses of the Oxford–AstraZeneca vaccine were delivered to Accra.
The work that remains
COVAX is currently working with governments, manufacturers and partners to ensure that when countries receive vaccines, they can get them to people quickly.
“The work that has gone into this (1 billion) milestone is only a reminder of the work that remains”, the UN’s health agency underscored.
They added that with updated vaccines in the pipeline, citizens should demand that governments and pharmaceutical companies share health tools globally and “bring an end to the death and destruction cycles of this pandemic, limit new variants and drive a global economic recovery”.
COVAX is one of three pillars of the Access to COVID-19 Tools (ACT) Accelerator, which was launched by WHO in April 2020 in response to the pandemic.
The ACT Accelerator is a ground-breaking global collaboration to accelerate the development, production, and equitable access to COVID-19 tests, treatments, and vaccines.
WHO recommends two new drugs to treat patients with COVID-19
The World Health Organization (WHO) on Thursday reccommended two new drugs to treat patients with COVID-19, one for patients with critical disease, and another deemed effective for non-severe cases.
The first drug, baricitinib, is a Janus kinase (JAK) inhibitor- a class of drugs used to treat autoimmune conditions, blood and bone marrow cancers, and rheumatoid arthritis.
According to the WHO Guideline Development Group, it is “strongly recommended” for patients with severe or critical disease in combination with corticosteroids.
The group of international experts based their recommendation on “moderate certainty evidence” that it improves survival and reduces the need for ventilation.
There was no observed increase in adverse effects.
The experts note that it has a similar effectas other arthritis drugs called interleukin-6 (IL-6) inhibitors. Because of that, when both drugs are available, they suggest choosing the best option based on cost, availability, and clinician experience.
It is not recommended to use both drugs at the same time.
The experts also advise against the use of two other JAK inhibitors (ruxolitinib and tofacitinib) for patients with severe or critical cases of COVID-19 infection.
According to them, trials undergone using these drugs failed to show any benefits arising using either drug,and suggested a possible increase in serious side effects with tofacitinib.
In the same update, WHO makes a conditional recommendation for the use of a monoclonal antibody known as sotrovimab in patients with non-severe cases.
According to them, the drug should only be administered to patients at the highest risk of hospitalisation. In those at lower risk, it onlyshowed “trivial benefits”.
A similar recommendation has been madepreviously, for another monoclonal antibody drug, casirivimab-imdevimab, and the experts say there is insufficient data to recommend one over the other.
For both, the effectiveness against new variants, like Omicron, is still uncertain.
The group will update their guidelines for monoclonal antibodies when more data becomes available.
These recommendations are based on new evidence from seven trials involving over 4,000 patients with non-severe, severe, and critical infections.
Developed by WHO with the methodological support of MAGIC Evidence Ecosystem Foundation, the guidelinesprovide trustworthy guidance and help doctors make better decisions with their patients.
According to the agency, the guidelines are useful in fast moving research areas, because they allow researchers to update evidence summaries as new information becomes available.
The latest guidance also updates recommendations for the use of interleukin-6 receptor blockers and systemic corticosteroids for patients with severe or critical COVID-19; conditional recommendations for the use of casirivimab-imdevimab (another monoclonal antibody treatment) in selected patients; and against the use of convalescent plasma, ivermectin and hydroxychloroquine, regardless of disease severity.
Omicron fuels record weekly COVID-19 cases, but deaths ‘stable’
Fuelled by Omicron, more than 15 million new cases of COVID-19 were reported around the world last week, by far the most cases reported in a single seven day period, the World Health Organization (WHO) informed on Wednesday.
Briefing reporters in Geneva, the UN health agency chief, Tedros Adhanom Ghebreyesus, said the “huge spike” is being driven by the Omicron variant, which is rapidly replacing Delta in almost all countries.
Despite the number of cases, the weekly reported deaths have “remained stable” since October last year, Tedros added, at an average of 48,000. The number of patients being hospitalized is also increasing in most countries, but it is not at the level seen in previous waves.
He told reporters this is possibly due to the reduced severity of Omicron, and widespread immunity from vaccination or previous infection.
‘50 thousand deaths too many’
For the WHO chief, while Omicron causes less severe disease than Delta, it remains a dangerous virus, particularly for those who are unvaccinated.
“Almost 50 thousand deaths a week is 50 thousand deaths too many”, Tedros said. “Learning to live with this virus does not mean we can, or should, accept this number of deaths.”
For him, the world cannot “allow this virus a free ride” when so many people around the world remain unvaccinated.
In Africa, for example, more than 85 per cent of people are yet to receive a single dose of vaccine.
“We cannot end the acute phase of the pandemic unless we close this gap”, he said.
Tedros then listed some progress towards reaching the target of vaccinating 70 per cent of the population of every country by the middle of this year.
In December, COVAX shipped more than double the number of doses it distributed in November. In the coming days, the initiative should ship its one billionth vaccine dose.
Some of the supply constraints from last year are also starting to ease, Tedros said, but there’s still have a long way to go.
So far, 90 countries have still not reached the 40 per cent target, and 36 of those countries have vaccinated less than 10 per cent of their populations.
Tedros also highlighted an interim statement from the WHO Technical Advisory Group on COVID-19 Vaccine Composition, released on Tuesday, stressing that further vaccines are needed that have a greater impact on preventing infection.
Until such vaccines are developed, the experts explained, the composition of current vaccines may need to be updated.
The Group also said that a vaccination strategy based on repeated booster doses is “unlikely to be sustainable.”
A heavy toll
According to Tedros, the overwhelming majority of people admitted to hospitals around the world are unvaccinated.
At the same time, while the immunizations remain very effective at preventing severe disease and death, they do not fully prevent transmission.
“More transmission means more hospitalizations, more deaths, more people off work, including teachers and health workers, and more risk of another variant emerging that is even more transmissible and more deadly than Omicron”, Tedros explained.
The sheer number of cases also means more pressure on already overburdened and exhausted health workers.
A study published last year showed that more than one in four health workers have experienced mental health issues during the pandemic. Data from several countries also show that many have considered leaving or have left their jobs.
On Tuesday, WHO hosted a global webinar, attended by clinicians from around the world, on the clinical management of the virus during pregnancy, childbirth and the early postnatal period.
As stated earlier in the pandemic, pregnant women are not at higher risk of contracting COVID-19, but if they are infected, they are at higher risk for severe disease.
“That’s why it’s vital that pregnant women in all countries have access to vaccines to protect their own lives, and those of their babies”, Tedros said.
The agency chief also called for pregnant women to be included in clinical trials for new treatments and vaccines.
He also stressed that, fortunately, mother to baby transmission in utero or during birth is very rare, and no active virus has been identified in breast milk.
Labour market recovery still ‘slow and uncertain’
As the COVID-19 pandemic grinds on and global labour markets continue to struggle, the latest International Labour Organization (ILO) report,...
India’s open invitation to a nuclear Armageddon
Army chief General Manoj Mukund Naravane said that “India was not averse to the possible demilitarisation of the Siachen glacier...
The role of CPC in supporting leadership schools in democratic countries
The Department of International Communication is officially under the Central Committee of the Communist Party of China “CPC”, known by...
Guterres Calls on Private Sector to Help Developing Countries with Post-Pandemic Recovery
In a special address at the virtual World Economic Forum Davos Agenda 2022 on Monday, United Nations Secretary-General António Guterres...
Modi Urges All Countries to Embrace Sustainable Lifestyles
Prime Minister Narendra Modi of India used his address to the Davos Agenda 2022 to call on all countries to...
China: $1.9 Trillion Boost and 88M Jobs by 2030 Possible with Nature-Positive Solutions
Nearly $9 trillion, two-thirds of China’s total Gross Domestic Product (GDP), is at risk of disruption from nature loss. Making...
UN-backed COVAX mechanism delivers its 1 billionth COVID-19 vaccine dose
With a 1.1 million jab delivery in Rwanda this weekend, the World Health Organization’s multilateral initiative to provide equal access...
Defense3 days ago
Why shouldn’t Israel Undermine Iran’s Conventional Deterrence
New Social Compact3 days ago
Age No Bar: A Paradigm Shift in the Girl Child’s Marriageable Age in India
Americas4 days ago
The Forgotten Analogy: World War II
Crypto Insights3 days ago
The Bitcoin ETFs: An Instrument to be Reckoned With
Crypto Insights4 days ago
Unifying Cryptocurrency ESG Efforts Key to Boost Global Adoption
Middle East3 days ago
Egypt vis-à-vis the UAE: Who is Driving Whom?
Science & Technology4 days ago
Ethical aspects relating to cyberspace: Self-regulation and codes of conduct
Economy3 days ago
Rebalancing Act: China’s 2022 Outlook