Connect with us

Health & Wellness

COVID-19: ‘Little or no’ benefit from trials of anti-virals

Published

on

A healthcare worker checks the temperature of a patient at a hospital in Nonthaburi Province, Thailand. UN Women/Pathumporn Thongking

Latest results from a UN-coordinated international trial on four COVID-19 therapeutic drugs, indicate that they have “little or no” positive impact on preventing deaths in patients infected with the new coronavirus. 

 The Solidarity Therapeutics Trial, overseen by the World Health Organization (WHO), shows that medications Remdesivir, hydroxychloroquine, lopinavir/ritonavir and interferon, repurposed to treat new coronavirus infections, “appeared to have little or no effect on 28-day mortality or the in-hospital course of COVID-19 among hospitalized patients”, WHO said in a statement on Friday. 

The study, which began in March and spans more than 30 countries, looked at the effects of these treatments on overall mortality, initiation of ventilation, and duration of hospital stay in hospitalized individuals.  

Other uses of the drugs, for example in treatment of patients in the community or for prevention, would have to be examined using different trials, the WHO explained. 

Associated blood pressure risks 

In a related announcement, the UN health agency said that COVID-19 had also highlighted the increased vulnerability of people with high blood pressure to the coronavirus. 

The warning is based on data from more than 120 countries showing significant COVID-related disruption to treatment for people suffering from chronic health conditions, with findings showing these patients make up 50 to 60 per cent of all deaths from COVID. 

Dr. Bente Mikkelsen, Director of WHO’s Department of Noncommunicable Diseases, said that more than 1.13 billion people around the world suffer from hypertension. 

Of this number, 745,800,000 live in low and middle-income countries and 80 per cent of these nations have fewer than 50 per cent of people on treatment. 

Many unaware they are sick 

On average, one in four men suffer from the condition, compared with one in five women, according to WHO data. In addition, two in five people are not aware that they even have hypertension. 

“When it comes to COVID-19 and hypertension, the 122 countries that have reported tells us that in over 50 per cent of the countries their health care services is disrupted fully or partially…In addition, we see a high number of fatalities”, Dr. Mikkelsen told journalists in Geneva. 

Noting that global figures have yet to be calculated, she added that for those countries where data was available, “we see in the range of 50, 60 per cent of the people that are severely ill and die in hospitals from COVID have hypertension, diabetes”, and other non-communicable diseases. 

Pandemic resurgence 

Highlighting how the pandemic has made a resurgence in many countries across all continents after the easing of restrictions, and the additional health threat posed by the impending influenza season in the global north, the WHO official appealed to governments everywhere to address hypertension urgently. 

She also cited growing evidence that poor and salty diets along with rising inactivity, have contributed to worsening hypertension rates globally. 

To coincide with World Hypertension Day on 16 October, Dr Mikkelsen unveiled a series of recommendations and products developed by the WHO to promote action on hypertension “during and beyond the pandemic”. 

By doing so, health authorities can help people to keep their blood pressure under control and prevent stroke, heart attack, and kidney damage, the WHO believes. 

The new protocols are based on successful patient blood pressure management in 18 countries involving more three million people. 

Today, only 20 per cent of the world’s nations are on track to reduce hypertension by 25 per cent by 2025, a global target set by the World Health Assembly in 2013, according to the UN health agency. 

Continue Reading
Comments

Health & Wellness

‘Digital dumpsites’ study highlights growing threat to children

Published

on

E-waste toxicants. Source: WHO

The health of children, adolescents and expectant mothers worldwide is at risk from the illegal processing of old electrical or electronic devices, the World Health Organization (WHO) said on Tuesday, in a landmark new report on the toxic threat. 

In a statement coinciding with the launch, WHO Director-General Tedros Adhanom Ghebreyesus warned that the health threat was growing, in line with the “mounting ‘tsunami of e-waste’”. 

“In the same way the world has rallied to protect the seas and their ecosystems from plastic and microplastic pollution, we need to rally to protect our most valuable resource –the health of our children – from the growing threat of e-waste”, he added. 

A growing pile 

Discarded electronic devices, or e-waste, has become the fastest growing domestic waste category in the world, according to the UN health agency.  

The Global E-waste Statistics Partnership (GESP) said that of the 53.6 million tonnes produced worldwide in 2019, only 17.4 per cent was recorded as collected and appropriately recycled.  

While the fate of the remaining e-waste is unknown, it is unlikely to have been managed and recycled in an environmentally-sound manner.  

Hazards on the heap 

While some e-waste ends up in landfills, significant amounts are often illegally shipped to low and middle-income countries where informal workers, including children and adolescents, pick through, dismantle, or use acid baths to extract valuable metals and materials from the discarded items. 

WHO said that an estimated 12.9 million women who work in the informal waste sector are potentially exposing themselves and their unborn children to toxic residue. 

Additionally, more than 18 million youngsters globally – and some as young as five – are said to be “actively engaged” in the wider industrial sector, of which e-waste processing is a small part.  

‘Devastating’ impact 

Informal methods of removing materials from e-waste have been linked to a range of health effects, especially in children, WHO said.  

Recycling e-waste particularly impacts those in vital stages of physical and neurological development, with children, adolescents and pregnant women most vulnerable. 

Children are more susceptible to the toxic chemicals because they absorb pollutants relative to their size and, with not-fully-developed organs, are less able than adults to eradicate harmful substances. 

“Improper e-waste management is…a rising issue that many countries do not recognize yet as a health problem”, said WHO lead author, Marie-Noel Brune Drisse, warning that if action is not taken now, “its impacts will have a devastating health effect on children and lay a heavy burden on the health sector in the years to come”.  

Call to action  

The Children and Digital Dumpsites report delves into the multiple dimensions of the problem, to practical action that the health sector and others concerned, can take to confront the insidious health risk.  

It calls for binding action by exporters, importers and governments to ensure environmentally sound disposal of e-waste and the health and safety of workers and communities. 

The health sector is also being asked to reduce adverse effects from e-waste by building up capacity to diagnose, monitor and prevent toxic exposure, and to advocate for better data and health research on risks faced by informal e-waste workers. 

“Children and adolescents have the right to grow and learn in a healthy environment, and exposure to electrical and electronic waste and its many toxic components unquestionably impacts that right”, said Maria Neira, WHO Director of the Department of Environment, Climate Change and Health.  

“The health sector can play a role by providing leadership and advocacy, conducting research, influencing policy-makers, engaging communities, and reaching out to other sectors to demand that health concerns be made central to e-waste policies.”

Continue Reading

Health & Wellness

Landmark G7 agreement pledges 870 million COVID-19 vaccine doses

Published

on

G7 leaders plenary: Building back better from COVID19, Cornwall, UK. ©Karwai Tang/G7 Cornwall 2021

A senior UN official welcomed on Sunday, the Group of Seven (G7) leading industrialized nations’ commitment to immediately share at least 870 million doses of COVID-19 vaccines, supporting global access and helping to end the acute phase of the pandemic. 

“Equitable access to COVID-19 vaccines represents the clearest pathway out of this pandemic for all of us — children included, and commitments announced by G7 members…are an important step in this direction”, the Executive Director of the UN Children’s Fund (UNICEF), Henrietta Fore, said in a statement

Building on the momentum of the G20 Global Health Summit and the Gavi COVAX AMC Summit, in a landmark agreement at the G7 Summit – underway in Cornwall, United Kingdom – the global leaders made the pledge, with the aim of delivering at least half by the end of 2021  

Secretary-General António Guterres had previously said that despite “unequal and very unfair” access to inoculations, “it is in the interest of everybody that everybody gets vaccinated sooner rather than later”.  

The G-7 leaders also reaffirmed their support for the UN-led equitable vaccine distribution initiative COVAX, calling it “the primary route for providing vaccines to the poorest countries”. 

Prompt action, please 

The COVAX alliance, meanwhile, welcomed the G7’s commitment, including their continued support for exporting in significant proportions and for promoting voluntary licensing and not-for-profit global production. 

The partners look forward to “seeing doses flowing to countries” as soon as possible.  

COVAX will work with the G7 and other countries that have stepped up to share doses as rapidly and equitably as possible to help address short-term supply constraints currently impacting the global response to COVID-19 and minimize the prospect of future deadly variants. 

“We have reached a grim milestone in this pandemic: There are already more dead from COVID-19 in 2021 than in all of last year”, lamented Ms. Fore. “Without urgent action, this devastation will continue”. 

Aligning interests 

Noting the need for a “ramp up”, in both the amount and pace of supply, the top UNICEF official attested that when it comes to ending the COVID-19 pandemic, “our best interests and our best natures align. This crisis will not be over until it is over for everyone.” 

The Director General of the World Health Organization (WHO), Tedros Adhanom Ghebreyesus, underscored that many countries are facing a surge in cases, without vaccines.  

“We are in the race of our lives, but it’s not a fair race, and most countries have barely left the starting line”, he said.  

While grateful for the generous announcements of vaccine donations, he stressed, that “we need more, and we need them faster”. 

Time of the essence 

As many high-income countries begin to contemplate post-vaccination life, the future in low-income countries appears quite bleak.  

“We are particularly worried about the surges in South America, Asia and Africa”, said the UNICEF chief. 

Moreover, as the pandemic rages, the virus mutates and produces new variants that could potentially threaten the vaccinated and unvaccinated alike.  

“Donating doses now is smart policy that speaks to our collective best interests”, she continued, adding that in addition to vaccine pledges, “distribution and readiness need clear timelines” as to when they will be available, particularly in countries with poor health infrastructure. 

“The COVID-19 pandemic has upended the lives of children, affecting every aspect of their lives: their health, education, protection and future prosperity. Now, more than ever, what we do today will have significant and lasting impact on our collective tomorrows. There is no time to waste”, she concluded. 

Explanations 

The G7 is made up of Canada, France, Germany, Japan, Italy, UK and United States. 

COVAX was set up by WHO, GAVI the vaccine alliance and the Coalition for Epidemic Preparedness Innovations (CEPI). It is part of the Access to COVID-19 Tools (ACT) Accelerator to equitably provide COVID-19 diagnostics, treatments and vaccines to all people globally, regardless of their wealth. 

Continue Reading

Health & Wellness

Vaccine inequity triggers ‘huge disconnect’ between countries

Published

on

Although COVID-19 cases and deaths continue to decline globally for a second consecutive week, the UN health agency chief said on Monday that “a huge disconnect” is mounting between some highly vaccinated countries, which see the pandemic as largely resolved, while huge waves of infection continue to grip others where shots are scarce. 

“The pandemic is a long way from over, and it will not be over anywhere until it’s over everywhere”, Tedros Adhanom Ghebreyesus, Director-General of the World Health Organization (WHO) told journalists once more, at the regular press briefing in Geneva. 

Still under threat 

Tedros pointed to “dramatic increases” in cases, hospitalizations and deaths, in places where the coronavirus had previously been contained and added that new variants, fragile health systems, relaxed public health measures – and shortages of oxygen, dexamethasone and vaccines – were compounding the problem. 

“But there are solutions”, he said, urging people to adhere to physical distancing, continue to wear masks and avoid large gatherings. “Even where cases have dropped, genetic sequencing is critical so that variants can be tracked and measures are not eased prematurely”. 

Urgent financial support needed 

Although WHO has been responding to the surge in India and other flashpoints, immediate additional funding is required to sustain support in all countries experiencing new waves of cases. 

The 2021 response plan is already underfunded, and the vast majority of it is “ring fenced” by donors for specific countries or activities, which is constraining WHO’s ability to provide “an adaptable and scalable response in emerging hotspots”, Tedros said. 

Urgent and flexible funding would allow the UN health agency to scale up support for countries and the ACT Accelerator.  

Set ambitious goals ‘collectively’ 

Meanwhile, the UN Children’s Fund (UNICEF) outlined a 190 million dose shortfall in the UN-backed COVAX vaccine initiative for equitable COVID inoculations. 

While COVAX has delivered 65 million doses to 124 countries and economies to date, the WHO chief called on manufacturers to publicly commit to sharing their vaccines with COVAX by lifting contractual barriers “within days not months”. 

He also pressed manufacturers to give the right of first refusal to COVAX on any additional doses and encouraged them to make deals with companies willing to use their facilities to produce COVID-19 vaccines. 

“We need to collectively set ambitious goals to at least vaccinate the world’s adult population as quickly as possible”, Tedros underscored. 

Road safety priorities 

Although pandemic lockdowns and telecommuting has led to fewer car journeys and road crashes, the WHO chief pointed to a converse problem caused by drivers’ speeding. This has meant the number of deaths had not decreased proportionately.  

Kicking off UN Road Safety Week, Tedros asked for national and local policy commitments “to deliver 30 kilometre per hour speed limits in urban areas and generate local support for low speed measures overall”. 

Addressing the risk of road traffic deaths is also fundamental to achieve the Sustainable Development Goals (SDGs), specifically those affecting health security, sustainable cities and reducing inequalities among and within countries.  

And policies that tackle the of impact road traffic, and create environments for safe, sustainable and inclusive transport options, also unlock action for protecting the climate and gender equality.  

A paradigm shift in how streets are designed can make streets safe, accessible and equitable for all road users – delivering multiple benefits while accelerating action across interlinking SDGs, according to WHO.

Continue Reading

Publications

Latest

Economy5 mins ago

Build Back Better World: An Alternative to the Belt and Road Initiative?

The G7 Summit is all the hype on the global diplomatic canvas. While the Biden-Putin talk is another awaited juncture...

Style2 hours ago

Dongyu Zhou wears Constellation

Award-winning Chinese actress Dongyu Zhou wears OMEGA’s Constellation Small Seconds. A winner of multiple domestic and foreign film awards, Dongyu...

Health & Wellness3 hours ago

‘Digital dumpsites’ study highlights growing threat to children

The health of children, adolescents and expectant mothers worldwide is at risk from the illegal processing of old electrical or...

Russia4 hours ago

Biden pushed China and Russia to rebel against one other

Biden’s anti-China measures have been increasingly regular in recent years. He not only continued to encircle China with his Asian...

Science & Technology6 hours ago

To Protect Democracies, Digital Resiliency Efforts Are Needed Now

Across the globe, more than three billion people have no internet access. But with the increased availability of smart phones...

Human Rights7 hours ago

Philippines: Investing in Nutrition Can Eradicate the “Silent Pandemic”

The Philippines needs to invest more in programs tackling childhood undernutrition to eliminate what is long considered a “silent pandemic”...

Africa Today8 hours ago

Sierra Leone Receives World Bank Support to Strengthen Education Service Delivery

Sierra Leone will receive $6.85 million in additional financing to support the COVID-19 education response in the country. Funded by...

Trending