European Commission has invited more than 200 blood-collection services around the EU to apply for funding for the purchase of plasmapheresis equipment, i.e. equipment that takes plasma from donors. The aim of this action is to support the treatment of new COVID-19 patients who are fighting the disease, by increasing EU capacity to collect convalescent plasma, i.e. plasma from recovered COVID-19 patients. This action is part of the Emergency Support Instrument (ESI). Grants will be provided to public and NGO blood-collection services authorised to collect plasma.
This action demonstrates the Commission’s commitment to developing therapeutics, as specified in the EU health preparedness for possible future outbreaks communication.
Stella Kyriakides, Commissioner for Health and Food Safety, said: “Convalescent plasma could be a promising treatment for COVID-19.With the financing we put forward today, we are able to go a step further in plasma collection and I invite all relevant stakeholders to make use of it. We will continue to explore all possible options to support the development and access to safe and effective treatments for COVID-19 to protect our citizens. This remains our primary objective in the weeks and months ahead.”
The treatment consists of transfusing convalescent plasma to sick patients to boost their immunity and ability to fight the disease. Plasma transfusion is also used to purify antibodies to make a COVID-19 specific medicinal product (immunoglobin) as short-term alternative to vaccines. This product is given as a prophylactic injection to patients, vulnerable persons and healthcare workers, or as a treatment. The efficacy of these treatments is being investigated worldwide, including in an EU research project funded by Horizon 2020. Preliminary results are promising while results from full clinical trials are forthcoming.
These treatments rely on the collection of large quantities of convalescent plasma donated by recovered patients.
At the moment, almost 75% of plasma collected by public blood services and the Red Cross is done via donations of whole blood, from which the plasma is then separated. This is a much less efficient collection method compared with plasmapheresis – a bedside process where plasma is taken from the donor whilst the other blood components are returned to the donor. In case of plasmapheresis, donors can donate higher volumes of plasma at one time and can donate once every 2 weeks compared with once every 3-4 months for whole blood donors. Additionally, ‘super donors’ – donors whose plasma is particularly rich in antibodies – can be asked to give donations many times over a period of months.
The invitation is valid for a month, and has a budget of €40 million funded through the Emergency Support Instrument. The allocation of grants will be done according to the needs expressed by Member States’ blood-collection services
The budget will support the purchase of a number of plasmapheresis machines and associated equipment, including collection kits, storage facilities, the testing and characterisation of plasma and organisational programmes.
Adopted by the Council in April 2020, the Emergency Support Instrument (ESI) allows the EU to provide emergency support addressing the human and economic consequences of a crisis such as the ongoing pandemic.
The ESI supports Member States in their efforts to address the COVID-19 pandemic in a strategic and coordinated manner at European level.
In the health area, the ESI is already being used to help address Member States’ ongoing needs and to contribute to preparedness for future outbreaks and a possible second wave. In particular, the ESI is supporting the transport of essential goods, medical teams and patients and is financing a facility to procure essential medical products for stockpiling and/or distribution to Member States.
Under the procurement facility, a contract was signed on 28 July to secure doses of the therapeutic Remdesivir for around 30,000 patients across the EU. Some 10 million masks to protect healthcare workers have also been purchased and delivery through batches is on-going.
A significant part of the budget available under the ESI will be used to secure the production of vaccines in the EU and sufficient supplies for its Member States through Advance Purchase Agreements with vaccine producers, in line with the EU Vaccines Strategy.
New WEF ESG initiative looks to improve socioeconomic conditions in Northern Central America
The World Economic Forum announced a new initiative in three Central American countries that will support the private sector apply Stakeholder Capitalism Metrics and better environmental, social and governance (ESG) reporting to improve local socioeconomic conditions and environmental resilience.
The announcement was made at events convened by the Forum with CentraRSE in Guatemala, COHEP in Honduras and Fundemas in El Salvador. These were attended by leaders from the public and private sector, civil society and international organizations who discussed the benefits and opportunities of implementing structured ESG reporting metrics, practices and global corporate trends. National and regional efforts and best practices were also showcased.
The Measuring Stakeholder Capitalism initiative has identified a set of 21 core and 34 expanded universal metrics and disclosures drawn from existing standards. The metrics and disclosure seek to improve how companies measure and demonstrate their performance against environmental, social and governance indicators and consistently track their positive contributions towards achieving the UN Sustainable Development Goals (SDGs).
Strengthening sustainability credentials and building the capacity to report this information will represent a significant advantage for businesses and the economy as a whole, particularly to attract foreign investment and integrate into regional and global value chains.
“Amid an increasingly challenging context confronted with overlapping global crises, public-private collaboration and the decisive action of local leadership are even more necessary to improve economic, social, environmental and governance conditions. All sectors must work together to build a prosperous and resilient ecosystem, offering hope and real opportunities for people in the region to develop their potential at home,” said Marisol Argueta, Head of Latin America at the World Economic Forum.
The initiative is a response The initiative is a response to US Vice President Kamala Harris’s Call to Action, which calls on businesses and social enterprises to promote economic opportunities for people in the region as part of a comprehensive strategy to address the root causes of migration. Vice President Harris has announced a total of more than $3.2 billion in new commitments to the region in coordination with the Partnership for Central America since the effort was launched in May 2022.
“As we look to multi-sector approaches to solve the social challenges facing our communities globally, the World Economic Forum’s ESG framework provides a structure for businesses to drive greater economic development. Working with public and private sector partners, this can translate into quality jobs, environmental protections and better lives for families,” said Jonathan Fantini-Porter, Executive Director of the Partnership for Central America.
The areas of focus, led by the Partnership for Central America (PCA), intend to support the region’s long-term development through digital and financial inclusion, food security and climate-smart agriculture; climate adaptation and clean energy; education and workforce development; and public health access. The planned ESG metrics and corporate reporting activities also aim to motivate local leaders to take measurable action on their contributions to enhancing socioeconomic conditions and environmental resilience in the region.
Based on existing standards, this framework provides a set of metrics that can be reported by all companies, regardless of industry or region. These metrics also offer comparability, which is particularly important for creating a systemic and globally accepted set of common standards for reporting corporate sustainability performance.
As part of the activities carried out in Central America, the Guatemalan company, Grupo Mariposa announced the adoption of the global metrics framework promoted by the World Economic Forum (Stakeholder Capitalism Metrics) and declared its commitment to include them in future reporting cycles. Grupo Mariposa is the first company in Central America to incorporate the metrics in its reports.
‘Immensely bleak’ future for Afghanistan unless massive human rights reversal
The international community must dramatically increase efforts to urge the de facto authorities in Afghanistan to adhere to basic human rights principles, a group of UN independent rights experts said on Friday.
“The future is immensely bleak for Afghans if more is not done by the international community to ensure the Taliban changes its modus operandi and complies with its human rights obligations,” they said in a statement.
The experts recalled that following the Taliban takeover last August, they had appealed for the international community to take “stringent actions” to protect Afghans from violations such as arbitrary detention, summary executions, internal displacement, and unlawful restrictions on their human rights.
Failure to deliver
“One year later, we reiterate this call,” they said. “Despite making numerous commitments to uphold human rights, the Taliban have not only failed to deliver on their promises, they have also reversed much of the progress made in the past two decades”.
Moreover, the humanitarian and economic crisis in Afghanistan, which has already caused immeasurable harm to millions, shows no signs of slowing down. In fact, it is predicted to worsen, they added, partly due to the interruption of international assistance and the freezing of Afghan assets abroad.
Attack on women and girls
The experts said the Taliban have committed a “plethora” of human rights violations, with the virtual erasure of women and girls from society, as well as their systematic oppression, being particularly egregious.
“Nowhere else in the world has there been as wide-spread, systematic and all-encompassing an attack on the rights of women and girls – every aspect of their lives is being restricted under the guise of morality and through the instrumentalization of religion. Discrimination and violence cannot be justified on any ground”.
Regrettably, there is little indication that the human rights situation is turning a corner, they said.
“Indeed, the daily reports of violence – including extra-judicial killings, disappearances, arbitrary detention, torture, heightened risks of exploitation faced by women and girls including for the purposes of child and forced marriage, and a breakdown in the rule of law – gives us no confidence that the Taliban has any intention of making good on its pledge to respect human rights.”
Citizens now have no means for redress as the Afghanistan Independent Human Rights Commission has been abolished, along with other independent oversight mechanism and institutions.
The administration of justice has also been compromised. The applicable law is unclear, and judges and other officials have been replaced, which has especially affected women.
Peace prospects dim
The experts pointed to other violations, such as the curtailing of press freedom, and the rise in attacks on religious and ethnic minorities, some of which were claimed by the ISIL-KP terrorist group. They also and highlighted how journalists, activists, academics and artists have either left the country, quit their work, or gone into hiding.
Furthermore, in the absence of an inclusive and representative government, prospects for long-lasting peace, reconciliation and stability will remain minimal.
“The de facto authorities seek international recognition and legitimacy. Regrettably, they continue to abuse almost all human rights standards while refusing to offer even a modicum of respect for ordinary Afghans, in particular women and girls,” said the experts.
Most recently, the Taliban appeared to have been harbouring the leader of Al Qaeda. Ayman al-Zawahiri was killed last week in a US drone strike, which the experts said also raises concerns of a violation of international law.
“Until it demonstrates significant steps towards respecting human rights, including by immediately reopening girls’ secondary schools and restoring their access to a quality education, they should not be on a path to recognition.”
Action by the authorities
In addition to honouring their international obligations, the experts have called for the Taliban to fully implement human rights standards, including respecting the rights of women and girls to education, employment and participation in public life.
The de facto authorities should immediately open all secondary schools for girls, and lift restrictions on women’s mobility, attire, employment and participation. The rights of minority communities must also be upheld.
The Taliban are also urged to “respect the general amnesty and immediately stop all reprisals against members of the former government’s security forces, other officials and civil society, especially human rights defenders, including women”.
Furthermore, human rights monitors and humanitarians should be allowed free, unhindered access throughout the country, including to sensitive locations such as detention facilities.
They also called for the Afghanistan Independent Human Rights Commission, bar associations, and other relevant unions, to immediately be reinstated and allowed to operate freely and independently.
The experts also outlined steps the international community should take.
They include insuring civilians have equitable access to humanitarian aid, and supporting ongoing initiatives by Afghan women towards a strategy to promote the rights of women and girls, with clear benchmarks and expectations.
Countries are also urged to maintain and/or adopt sustained and robust humanitarian exemptions within sanctions regimes to ensure compliance with international human rights and humanitarian law.
“Such measures should be fit for purpose, ensure that sanctions measures do not interfere with protected humanitarian action under international law, and function to remediate the current humanitarian crises and to prevent sanctions from continuing to exacerbate the humanitarian human rights crises being faced by the Afghan people,” they said.
Role of UN experts
The 20 experts who issued the statement were all appointed by the UN Human Rights Council.
They include Richard Bennett, UN Special Rapporteur on the situation of human rights in Afghanistan, and other Special Rapporteurs who monitor and report on issues such as the situation of human rights defenders worldwide.
These independent experts receive their mandates from the Council and operate in their individual capacity. They are neither UN staff, nor are they paid for their work.
IAEA: ‘Very alarming’ conditions at Ukraine’s Zaporizhzhia nuclear power plant
The situation at Ukraine’s Zaporizhzhia nuclear power plant has deteriorated rapidly to the point of becoming “very alarming,” Director General of the International Atomic Energy Agency (IAEA) Rafael Mariano Grossi warned the Security Council on Thursday afternoon.
“These military actions near such a large nuclear facility could lead to very serious consequences,” Mr. Grossi said at the meeting requested by Russia, which was marked by resounding calls to allow the Agency’s technical experts to visit the area amid mounting safety concerns.
IAEA has been in frequent contact with both Ukraine and Russia to ensure that it has the clearest picture possible of the evolving circumstances.
Europe’s largest nuclear plant shelled
Providing an overview, the IAEA chief said that on 5 August, the Zaporizhzhia plant – Europe’s largest – was subjected to shelling, which caused several explosions near the electrical switchboard and a power shutdown.
One reactor unit was disconnected from the electrical grid, triggering its emergency protection system and setting generators into operation to ensure power supply.
The senior UN official said that there was also shelling at a nitrogen oxygen station. While firefighters had extinguished the blaze, repairs must still be examined and evaluated.
No immediate threat
He said that the preliminary assessment of IAEA experts indicate that there is no immediate threat to nuclear safety as a result of the shelling or other military actions.
However, “this could change at any moment,” Mr. Grossi cautioned.
He recalled his recent address to the ongoing Tenth Review Conference of the Parties to the Nuclear Non-Proliferation Treaty, where he outlined seven indispensable pillars that are critical for nuclear safety and security.
These included aspects dealing with the physical integrity of the plant, off-site power supply, cooling systems, and emergency preparedness measures.
“All these pillars have been compromised if not entirely violated at one point or another during this crisis,” flagged the IAEA chief.
“Any nuclear catastrophe would be unacceptable and thus preventing it should be our overarching goal”.
He asked both sides to cooperate with the UN atomic agency.
“This is a serious hour, a grave hour, and the IAEA must be allowed to conduct its mission in Zaporizhzhia as soon as possible”.
Presenting his case, the Russian delegate said Ukrainian forces used heavy artillery against Zaporizhzhia on 5 August, shelling the plant during a shift change to intimidate staff – their own citizens.
He upheld that on 6 August, those forces attacked with cluster munitions, and on 7 August, a power surge occurred, blaming.
The Russian Ambassador blamed Kyiv for refusing to sign a trilateral document issued by IAEA, stressing that Moscow strictly complies with the IAEA Director General’s seven principles.
In turn, Ukraine’s representative said that the withdrawal of Russian troops and return of the station to the legitimate control of Ukraine is the only way to remove the nuclear threat at Zaporizhzhia.
The Ukrainian Ambassador insisted on the need to send a mission to the site and has negotiated modalities with the Agency.
“Despite their public declarations, the occupiers have resorted to manipulations and unjustified conditions for the site visit,” he said.
Given the militarization of the site by Russian armed forces, such a mission must include qualified experts in military aspects.
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